Drug Discovery Chemistry

Eleventh Annual
Drug Discovery Chemistry
Optimizing Small Molecules for Tomorrow's Therapeutics
April 19-22, 2016   |  San Diego, CA

Network with 600+ Colleagues at Drug Discovery Chemistry in San Diego
Attendance Up 20% Year-Over-Year

Breakout discussions are a unique and invaluable opportunity for attendees to network, collaborate and problem solve with experts in a particular research specialty. Participate at Drug Discovery Chemistry and benefit from 18 breakout discussions where you will be able to:

  • Meet potential collaborators
  • Share examples of your work
  • Vet ideas with your peers
  • Be part of a group problem-solving endeavor

Register  [Save up to $200, Register by March 11]

Breakout Discussion Details  |   Present a Poster  |  Sponsorship & Exhibits  |  Short Courses  |  Brochure


Breakout Discussions at Drug Discovery Chemistry
Inflammation Inhibitors
Kinase Inhibitor Chemistry

Developing Kinase Inhibitors for Chronic Indications
Moderator: Kamal Puri, Ph.D., Senior Principal Scientist, Immunology & Inflammation, Celgene Corp.

What Can Medicinal Chemists Do Better to Discover Safe and Effective Anti-Inflammatory Therapeutics?
Moderator: Jennifer Venable, Ph.D., Associate Scientific Director, Medicinal Chemistry, J&J

Targeting Innate Immunity
Moderator: Robert Hughes, Ph.D., Senior Associate Director, Small Molecule Discovery Research, Boehringer-Ingelheim

Emerging Kinase Inhibitor Design Paradigms
Moderator: Gerhard Mueller, Ph.D., Senior Vice President, Medicinal Chemistry, MercaChem BV

Best Practices for the Discovery and Development of Allosteric Modulators
Moderator: Ravi G. Kurumbail, Ph.D., Research Fellow and Structural Biology Laboratory Head, Pfizer

Blood Brain Barrier (BBB) Penetration with Kinase Inhibitors
Moderator: Paul Galatsis, Ph.D., Senior Principal Scientist, Worldwide Medicinal Chemistry, Pfizer

Protein-Protein Interactions
Macrocyclics & Constrained Peptides

How/When to Embark on a Covalent Inhibitor Strategy
Moderator: Daniel A. Erlanson, Ph.D., Co-Founder, Carmot Therapeutics, Inc.

PPI Approaches for Ubiquitin Regulated Proteins
Moderator: Han-Jie Zhou, Ph.D., Senior Director of Chemistry, Cleave BioSciences

Challenges in Targeting PPIs
Moderator: Laura Silvian, Ph.D., Principal Scientist, Cell and Protein Sciences, Biogen

Targeting PPIs with Macrocyclics
Moderator: Dehua Pei, Ph.D., Professor, Department of Chemistry and Biochemistry, The Ohio State University

Macrocyclic Library Challenges
Moderator: Scott Lokey, Ph.D., Professor, Chemistry and Biochemistry, University of California, Santa Cruz

The Extra Challenge of Lead Optimization with Macrocycles
Moderator: Alan M. Mathiowetz, Ph.D., Director, Pfizer Worldwide Medicinal Chemistry - Cardiovascular and Metabolic Diseases

Epigenetic Inhibitor Discovery
Fragment-Based Drug Discovery

Next-Generation BET Bromodomain Inhibitors
Moderator: Eric Campeau, Ph.D., PMP, Director of Biology, Zenith Epigenetics Non-BET

How Can We Identify New Inhibitors and Biomarkers for Histone Methyltransferases?
Moderator: Matthew Fuchter, Ph.D., Reader, Chemistry, Department of Chemistry, Imperial College London

Challenges in Targeting Histone Demethylases
Moderator: Takayoshi Suzuki, Ph.D., Professor, Graduate School of Medical Science, Kyoto Prefectural University of Medicine

Structuring Academic/Industry Partnerships
Moderators: Adam Renslo, Ph.D., Associate Professor, Department of Pharmaceutical Chemistry, University of California San Francisco
Chris Smith, Ph.D., Director, Medicinal Chemistry, COI Pharmaceuticals

Making Sense of Conflicting Data
Moderator: Ben Davis, Ph.D., Research Fellow, Biology, Vernalis Research

"Starting a Start-Up"
Moderator: TBA

Short Courses
Make the most of your time in San Diego by adding on one or more short courses*. Topics include trends in physical properties, GPCRs, peptide therapeutics, immunology, phenotypic screening, crystallography, ligand-receptor molecular interactions, inhibitor design, macrocycles, FBDD, and covalent inhibitors.
* separate registration required for short courses

Training Seminar
Led by Dr. Terry Kenakin, Applying Pharmacology to New Drug Discovery will describe pharmacological principles and procedures to quantify affinity, efficacy, biased signaling and allostery to better screen for new drugs and characterize drug candidates in lead optimization assays.

Sponsorship & Exhibits
The 2015 conference featured 500 participants from more than 25 countries. For exhibit & sponsorship information, including sponsored podium presentations, please contact Carolyn Benton at 781-972-5412.